Abstract
The antioxidant activities of water extract (WE), ethanol extract (EE), residue water extract (RWE) and petroleum ether (PF), ethyl acetate (EF), n-BuOH (BF) and water (WF) fractions of the ethanol extract from Eupatorium Lindley DC were investigated for the first time. Total phenolics content, DPPH radical scavenging activities, superoxide radical scavenging activities, total reduction capability, and ferrous ions chelating activities were determined for all the extracts and fractions. The results showed that all the extracts and fractions exhibited antioxidant activities with different magnitudes of potency. Among all the samples, WE and RWE exhibited the best antioxidant capacities, the BF also exhibited high antioxidant abilities in all tests except for the metal chelating activity, while the other extracts and fractions were relatively weak antioxidants. The BF had the highest total phenolics contents in all extracts and fractions, and the WE and RWE were found to be rich in tannins. Furthermore, the content of total phenolics showed good correlation with DPPH radical scavenging activity, superoxide anion radical scavenging activity, and the reducing power. Phenolic composition of all the extracts and fractions was identified and quantified by HPLC. The results indicate that the extracts of E. Lindley DC might be a useful potential source of natural antioxidant ingredients.
Highlights
It is well known that reactive oxygen species (ROS) can cause various diseases, such as cancer, cardiovascular disease, inflammatory injury and neurodegenerative disorders [1,2,3]
The results suggest that polar solvents were more suitable to extract the phenolic compounds from E. lindleyanum DC
The results indicated that total phenolics were the major contributors to the total reducing power of extracts from E. lindleyanum DC
Summary
It is well known that reactive oxygen species (ROS) can cause various diseases, such as cancer, cardiovascular disease, inflammatory injury and neurodegenerative disorders [1,2,3]. In addition there are health risks in the chronic consumption of synthetic antioxidants [4], thereby increasing interest in screening for natural antioxidants from plants and other bioresources [5,6,7,8,9]. Eupatorium lindleyanum DC is a traditional Chinese herb. Its aerial part, called ‘Yemazhui’, is mainly used for the treatment of chronic bronchitis, tracheobronchitis, hypertension, cold and fever, cough with sputum, headache, tonsillitis, bacillary dysentery, etc [10]. Ji et al [11] further reported the antimicrobial effects of a decoction of E. lindleyanum DC. Phytochemistry studies [10,12,13,14,15]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
