Abstract
Antinuclear antibody detection by indirect immunofluorescence is used as screening testing marker for autoimmune diseases in clinical laboratories. Two articles published in this issue of Chinese Journal of Laboratory Medicine are based on a long-term routine ANA testing of the clinical laboratory in Peking Union Hospital. Their results suggested that reference interval should be established in each clinical laboratory based on the reagent and detection system used. It will play a key role for improving clinical application value of ANA detection to set up a detection procedure for ANA and give a reasonable explanation of results. Key words: Antibodies; antinuclear; Immunofluorescence antibody technique; indirect; Autoimmune disease
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