Abstract
Tea tree oil (TTO), derived from M. alternifolia, has been widely used as an antimicrobial agent. Nanoparticles show completely new or improved properties based on specific characteristics such as particle size, distribution, and morphology. It can also enhance the stability of the oil, preventing or reducing the volatilization. In this way, the antimicrobial activities of TTO nanoparticles were evaluated against six Mycobacterium and eleven fungal species. TTO and TTO nanoparticles were active against both bacteria and fungi with MICs ranged from 0.002 to 2.5 %. The results showed that TTO nanoencapsulation maintains TTO activity, indicating that the use of nanotechnology may represent an alternative for the treatment of mycobacterial and fungal diseases.
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