Abstract
Abstract: Enterococcus faecalis is a common opportunistic pathogen that can infect various tissues in the human body and in particular, the oral cavity. It has been implicated in periodontal disease, oral mucosal lesions in immunocompromised patients, peri-implantitis, peri-radicular abscesses, and root canal infections. They are also most prevalent in secondary endodontic infections and are recognized as treatment-resistant bacteria in the root canal. Virulence factors help in this pathogenicity as some factors aid its adherence to the surface. It has become a research focus in recent times for its resistance to various antibiotics like vancomycin and so, the search for alternative therapeutic approaches has also evolved. Although various chemical irrigants such as sodium hypochlorite (NaOCl), chlorhexidine (CHX), iodine potassium iodide (IKI), calcium hydroxide (Ca(OH)2) and chlorine dioxide (ClO2) have been used for years, the use of plant extracts and essential oils have attracted the researchers to explore their activity against various dental pathogens like E. faecalis. Recently, it has been found that the phages are more effective in treating biofilm than antibiotics and it has also been observed that they are effective when used in combination with antibiotics. In this review, we have presented various treatment strategies that have been in use for treating dental infections and also discussed future therapeutic approaches, which, may help unfold promising novel strategies.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.