Abstract
Cancer patients undergoing chemotherapy are highly prone to infections because of suppression of their immune system. in the present study, the activity of fluoro-quinolones, cephalosporins, glycopeptides and oxazolidinones was evaluated in Staphylococcus aureus strains by broth dilution method according to Clinical and laboratory Standards institute (CLSI), USA guidelines. The frequency of methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) strains was 67% and 33% respectively. the MIC50 and MIC90 of isolates were ciprofloxacin 8 and 32 μg/ml for MRSA, 8 and 16 μg/ml for MSSA, levofloxacin 8 and 16 μg/ml for MRSA and MSSA, gatifloxacin 4 and 16 μg/ml for MRSA and 4 and 8 μg/ml for MSSA. MIC50 and MIC90 of vancomycin and linzolid were 1 and 2 μg/ml, 2 and 4 μg/ml for both MRSA and MSSA strains respectively. This study shows a high prevalence of and resistance in MRSA. However, vancomycin and linezolid were highly active and could be used for treating MRSA infections.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
