Abstract
Antibiotic resistance is a worldwide public health problem that requires urgent global attention and Gram-negative bacilli of the family are well-known for demonstrating drug resistance. These drug resistance microorganisms cause recurrent infections in patients in hospital units, limiting treatment alternatives and increasing morbidity and mortality rates. A cross sectional study was carried out in the Department of Microbiology, Santosh Medical College and Hospital Ghaziabad. 150 Gram negative bacteria isolated from various clinical samples from both IPD and OPD patients were included in this study.Among the Gram negative bacterial isolates maximum isolates were identified as (50%), s (20%), (12%), (10%),(07%) and (04%). were sensitive to Imipenem (82.2%), Gentamycin (55.5%), Cefepime (42.2%), and resistant to Ampicillin (85.9%), Ceftriaxone (82.9%) and Levofloxacin (62.9%).Routine surveillance of baseline resistance, expressing of hospital antibiotic policy and compliance with current guidelines will go long way in reducing multi drug resistance among pathogens.
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