Abstract
Recently, heterocyclic compounds and amino acids are of great interest to researchers owing to their various biological activities like; antimicrobial, anticancer, antiviral, anti-inflammatory, etc. Isatin is also a vital moiety containing N and O donor heteroatoms, and its Schiff base is used for complexation with metal ions which may alter their activities. The new metal complex of Ni has been synthesized using two ligands, 3-(2-phenylhydrazono) indolin-2-one (PHI) (L1) and amino acid Histidine (L2). The newly prepared ligand and the complex are further characterized by determination of molecular weight, element analysis, magnetic moment measurement, UV- visible, 1H NMR, and FTIR spectroscopy. The prepared compounds are examined for antimicrobial evaluation against several strains of bacteria and fungi.
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