Abstract

Medicinal plants have been used for centuries as remedies for human diseases because they contain components of therapeutic value.Herbal medicine is still mainstay of about 75-80 % of the whole population, mainly in developing countries, for primary health care because of better cultural acceptability, better compatiability with the human body and fewer side effects.Euphorbia hirta (amman pacharisi) is a small perennial herb which belongs to the family of Euphorbiaceae and it is used to treat bronchitic asthma, ameoboidal dysentry and laryngeal spasm.Pedalium murex (yanai nerunjil) is a much-branched annual herb. This belongs to the family of Pedaliaceae and is used to treat gonohorrea, urinary track infections and spermatohorrea.The present study is to compare the antibacterial and antifungal activity of aqueous and organic solvent leaf extracts of Euphorbia hirta and Pedalium murexThe antimicrobial assay is done by disc diffusion method []against bacterial species (Pseudomonas putida, Pseudomonas aeruginosa, Klebsiella pneumoniae, Aeromonas liquefaciens and lcaligenes spp.) and fungal species (Aspergillus niger, Aspergillus flavus, Aspergillus fumigatus, Aspergillus erythrocephalus and Fusarium spp.).

Highlights

  • Euphorbia hirta is a pantropical weed, possibly native to India

  • The leaves of both plants [Euphorbia hirta and Pedalium murex] were surface sterilized with running tap water (3 times) and soaked in 0.1% mercuric chloride solution

  • Diethyl ether extracts of both plants was inactive against tested bacterial strains

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Summary

Introduction

It is a hairy herb that grows in open grasslands, roadsides and pathways. It is widely used as a medicinal herb in most places it grows. There is no evidence to support this claim (Srinivas et al, 2011, Yoganarasimhan S.N. 2000) Pedalium is a genus of plant in the Pedaliacae family comprising one species, Pedalium murex. It is distributed in India, Sri Lanka and Tropical Africa.

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