Abstract

The present study has been targeted towards; investigation of molecular epidemiology and analysis of antibiotic resistance in different bacterial sp. Total 120 new bacterial isolates has been obtained having majority of bacteria Enterococcus sp. from 4 regional hospitals of 92 patients. The antimicrobial susceptibility test has been performed using 18 different antibiotics and resistant strains have been analyzed. Additionally, the isolated strains were tested for antibiotic resistance and polymerase chain reaction (PCR) has been performed for van A and van B genes. In the series of antimicrobial bacterial species Enterococcus sp. has emerged as one of the potential cause to raise the healthcare problems. This study has significant impact on such kind of molecular epidemiology investigations and may be useful in producing the basic knowledge on the local microorganism to refine and resolve the antimicrobial resistance issues faced by hospitals in the world.

Highlights

  • Enterococci are common type of bacteria, generally found in the organ of both animals and humans

  • Isolates were identified from out patients suffered earlier with number of diseases mainly categorized in infection caused disease like, urinary tract infection (UTI), respiratory tract infection, pregnancy as well as gastrointestinal tract infection

  • E. faecalis is one of the most common dominating species genus identified in isolated hospital-associated associated infections due to resistance to a broad range of antibiotics [20]

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Summary

Introduction

Enterococci are common type of bacteria, generally found in the organ of both animals and humans. These bacteria are capable to grow in any kind of adverse climatic conditions. During last few years Enterococci have grown through different mutation process, resulting as the most prevalent nosocomial pathogens. It is responsible for many infections in community as well as hospital infections such as urinary tract infection, life threating bloodstream infections, meningitis and endocarditis [4,5]

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