Abstract
Antimicrobial resistance (AMR) has been recognized by global leadership as the biggest - and the harshest challenge to the economic development of the humanity and the global health security. Factors responsible for burgeoning AMR are well known. Possible avenues for rapid containment of this scourge have also been articulated. Huge resources -both financial and technical are needed by the developing countries. In the absence of these, innovative cost-effective approaches are needed. Universal health coverage, and One Health approach that brings together human health, animal health and environmental impact to benefit health should be considered by resource-limited countries to implement in their countries with appropriate modifications that provide them with the best outcomes for their populations by preserving efficacy of currently available and affordable antimicrobial agents against infectious diseases.
Highlights
Antimicrobial resistance (AMR) has been globally recognized as one of the largest and harshest challenges to global health security and economic development
Due to slowed development of new antimicrobials, very few antimicrobials are left to effectively treat infections caused by multidrug-resistant pathogens, and still fewer that are affordable in the developing world [2]
An example is the swift spread of the New Delhi metallo-beta-lactamase-1 (NDM-1) producing Escherichia coli from India to the UK, Sweden, Austria, Belgium, France, Netherlands, Germany, the United States, Canada, Japan, China, Malaysia, Australia and Korea [3]
Summary
Antimicrobial resistance (AMR) has been globally recognized as one of the largest and harshest challenges to global health security and economic development. Immense gains of antimicrobial agents in the past eight decades may be negated by the emergence and spread of resistant malaria and common bacterial infections, including healthcare-associated infections, which account for high morbidity, mortality and economic loss in resource-limited countries with weak infection control practices [5]. Few Asian countries have efficient surveillance systems to detect and monitor trends in antimicrobial resistance or antimicrobial use across human, animal and food production sectors.
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