Antimicrobial prophylaxis in surgery: A synopsis

Abstract

Prophylactic antimicrobials are not routinely required. The use of specific antimicrobials depends on the type of procedure and the bacteria encountered. The agent should be given prior to the procedure in order to reach the tissue before contamination occurs. The level of the agent should be maintained throughout the procedure and the duration of prophylaxis should be brief. The antibiotic used should be stopped when the risk of contamination is over, usually not longer than 24–72 h. The use of newer generation antimicrobials is not indicated until further clinical studies demonstrated distinct advantages over the older antibiotics.