Abstract

Testosterone, epiandrosterone, dehydroisoandrosterone and androsterone have been examinedin vitro for antibacterial activity againstStaphylococcus aureus, S. epidermidis, Listeria monocytogenes, Streptococcus faecalis, Escherichia coli, Alcaligenes faecalis, andSalmonella paratyphy. Turbidimetric and manometric techniques were used to assay the antibacterial activity of the above androgens. Antibacterial action was shown by epiandrosterone and dehydroisoandrosterone only against the gram-positive microorganisms when they were grown in tryptic soy broth containing 10 to 20µg of hormone per ml.

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