Abstract
This research concerns the antimicrobial properties of an essential oil of a wild plant, Prangos asperula Boissier, and the determination of its toxicity threshold.Antimicrobial properties were tested against five germs Streptococcus fecalis, Staphylococcus aureus (gram positive bacteria) Salmonella typhi, Escherichia coli (gram negative bacteria) Candida albicans (yeast). The toxic effect of this essential oil was tested on mice in a laboratory. Different concentrations of the essential oil were used, ranging from 20 to 160 μl/ml. Each was tested on a series of five mice. After essential oil solution injection, the behavior of the mice was documented. The lethal dose (LD50) was deduced from the straight line describing the death rate in relation to the concentration of injected essential oil solution. The LD50 found was about 1,05 μmL/g.
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