Abstract

The medicinal value of earthworms has been known for centuries. The earthworms are the source of proteins, peptides, enzymes and physiologically active substances. Thus in the present study, the earthworm skin extracts were prepared and subjected to antimicrobial activity which was determined by the agar well diffusion method. The antimicrobial substances showed activity against Serratia marcescens. The molecular weight of the peptide from skin extract was found to be ~3kDa by SDS – PAGE and confirmed by zymogram analysis. Further the earthworm was identified by morphological and COI gene sequence analysis and resulted to be Wegeneriona sp. This study may lead to the formulation of new antimicrobial drug from the earthworm skin extract.

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