Abstract
AbstractCurcumin, a hydrophobic phenolic compound isolated from tumeric (Curcuma longa), has gained a great attention due to its health benefits and antimicrobial effects. In this study, curcumin nanoparticles (CNPs) were formulated via acusto‐plastic deformation technique, with three differently surface‐charged surfactants‐sodium dodecylsulfate, Tween 20 and cetrimonium bromide (CTAB). The fabricated CNPs were evaluated for their antimicrobial activity against Listeria monocytogenes, one of the most severe foodborne pathogens. Our results demonstrated that the CNPs formulated with positively charged surfactant (CTAB) exhibited the highest antimicrobial activity against L. monocytogenes, indicating that there is a strong relationship between surface charge and antimicrobial activity of curcumin. The enhanced antimicrobial action of CNPs‐CTAB was concluded to be due to the increased cell‐antimicrobial interaction, which resulted from the opposing electrical charges between CNPs‐CTAB and L. monocytogenes cells, as well as increased antimicrobial penetration endowed by the small size.Practical applicationsIn this study, we showed that surface charge as well as the small size of curcumin nanoparticles play a key role in enhancing cell‐antimicrobial interaction and antimicrobial efficacy. The fabricated CNP‐CTAB showed the best antimicrobial activity against Listeria monocytogenes. A size reduction to nano‐scale is a recently developed strategy used to improve drug/food delivery and matching the public demand for effective and safe antimicrobial formulations for control of foodborne pathogens.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.