Abstract
Nanotechnology is expected to open new avenues to fight and prevent disease using atomic scale tailoring of materials. The metallic nanoparticles is the most promising nanomaterials with antibacterial properties and which exhibit increased chemical activity due to their large surface to volume ratios and crystallographic surface structure. This work focuses on the antibacterial activity of TiO2 against drug-resistant bacteria and Candida albicans. The antibacterial activity of TiO2 was evaluated using the determination of minimum inhibitory concentration (MIC) by the dilution method on agar medium. The obtained results show a significant antibacterial activity on the strains tested: Pseudomonas aeruginosa ATCC27853: 0.5 μg/mL, Staphylococcus aureus ATCC29213: 64 μg/mL, Escherichia coli ATCC25922: 128 μg/mL and Candida albicans 0.5 μg/mL. The Titanium Dioxide nanoparticles appear to be attractive candidates of choice to be an effective alternative to antibiotics and pave the way for a promising new strategy antibacterial nanoscale.
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