Abstract
Dental caries is an infectious disease of teeth which end up in the destruction of dental hard tissue. Poor oral hygiene is one of the major factor for accumulation of microorganisms and their harmful effects. The current study was done on antimicrobial efficacy of different brands of toothpastes against organisms isolated from patients having dental caries and comparative analysis has been made between chemical and herbal based toothpastes. Primary screening of organisms had been carried out on sterile Nutrient Agar medium and five isolates (A1, A2, A3, A4 and A5) were obtained. Antimicrobial activity of toothpastes was checked using Agar well diffusion assay. In chemical based toothpastes, Close-up showed the maximum zone of inhibition of 30mm against A1 isolate and minimum efficacy was observed with Pepsodent with zone of 7mm against A4 isolate. In herbal based toothpastes, Babool showed highest effectiveness with zone of 28mm against A3 isolate and minimum with zone of 10 mm with Dabur red and Himalaya against A1 and A3 isolate. The comparative analysis showed that chemical based toothpastes are more effective than herbal based toothpastes. Further studies on probiotic approach should be done which has been a popular method used to affect oral microbial community.
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