Antimicrobial effect of marigold leaves extracts on periodontal pathogens: Invitro study

Abstract

Aim and objective: The aim and objective of this study was to assess the efficacy of Calendula officinalis (Linn.) with commercially available chlorhexidine gel and tetracycline fibers against plaque bacteria so that it can eventually be incorporated into periodontal anti-infective therapy. Materials and method: Plant extract was made by 10 grams of Preparation of plant extract dried and ground leaves were mixed with 100ml of methanol and ethanol used for the extraction. Periodontal ab plus and Hexi gel was used. Antibacterial activity for plaque sample was seen using agar well diffusion method. Results: Minimum Inhibitory Concentration of plaque bacteria at 0.1g/mL by Calendula officinalis (Linn.) was 15mm, chlorhexidine gel was 18mm and Periodontal ab plus was 33mm. periodontal ab plus showed 51 percent more zone of inhibition than C. officinalis leaves extracts and 42 percent more that of chlorhexidine gel. Conclusion: The results of the present study indicate that the C. officinalis extract possessed good antimicrobial potential. This study exhibited the significant antibacterial effect of C. officinalis but less than chlorhexidine gel and tetracycline fibers on plaque bacteria.