Abstract
High frequencies of antimicrobial drug resistance were observed in O157 and non-O157 Shiga toxin–producing E. coli strains recovered from patients in Michigan during 2010–2014. Resistance was more common in non-O157 strains and independently associated with hospitalization, indicating that resistance could contribute to more severe disease outcomes.
Highlights
High frequencies of antimicrobial drug resistance were observed in O157 and non-O157 Shiga toxin–producing E. coli strains recovered from patients in Michigan during 2010–2014
Most infections are caused by O157 strains; non-O157 Shiga toxin–producing Escherichia coli (STEC) infections have increased [2]
Given the importance of resistance in E. coli pathotypes, we sought to determine the prevalence of resistant STEC infections and assess the effects of resistance on disease
Summary
High frequencies of antimicrobial drug resistance were observed in O157 and non-O157 Shiga toxin–producing E. coli strains recovered from patients in Michigan during 2010–2014. Most infections are caused by O157 strains; non-O157 STEC infections have increased [2]. We obtained 358 STEC isolates from the Michigan Department of Health and Human Services (MDHHS) Reference Laboratory (Lansing, MI, USA), collected during 2010–2014.
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