Abstract
We analyzed 1,093 Vibrio cholerae isolates from the Democratic Republic of the Congo during 1997–2012 and found increasing antimicrobial drug resistance over time. Our study also demonstrated that the 2011–2012 epidemic was caused by an El Tor variant clonal complex with a single antimicrobial drug susceptibility profile.
Highlights
Cholera and dysentery have afflicted humankind for centuries
The two most common types of epidemic diarrhea in developing countries are watery diarrhea caused by Vibrio cholerae serogroup O1 and bloody diarrhea caused by Shigella dysenteriae serotype 1 (Sd1)
For quality control of Desoxycholate citrate agar (DCA), the following organisms should be adequate for confirmation of selective and inhibitory growth characteristics: E. coli may be somewhat inhibited, depending on the particular formulation used, but will produce pink colonies surrounded by a zone of precipitated bile; S. flexneri and S. dysenteriae 1 will produce fair to good growth of colorless colonies
Summary
Cholera and dysentery have afflicted humankind for centuries. The epidemics they cause have affected the outcome of wars and the fates of countries. Two etiologic agents are responsible for most epidemic diarrhea: toxigenic Vibrio cholerae serogroup O1, which causes watery diarrhea, and Shigella dysenteriae serotype 1, which causes bloody diarrhea. Two additional organisms have emerged to cause epidemic diarrhea, Vibrio cholerae serogroup O139, which causes watery diarrhea, and Escherichia coli serotype O157:H7, which causes bloody diarrhea. The latter is a common agent of diarrhea only in developed countries. The procedures described are not new; most have been used for a number of years These procedures were selected for testing specimens from outbreaks rather than for general use in a clinical microbiology laboratory.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
