Abstract
Monte Carlo simulations are used to determine the probability of attaining prespecified pharmacokinetic-pharmacodynamic (PK-PD) targets. Researchers in Texas recently performed such simulations to evaluate the current susceptibility breakpoints for 13 antimicrobials (21 dosing regimens) against Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter baumannii . Analysis of percent PK-PD target attainment for dosing …
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