Abstract
Objective: assessing antimicrobial activity of toothpastes with different ingredient composition recommended for infants and toddlers. Materials and Methods. The study object was dental plaque of children with decompensated form of caries under the age of 3 years old. Seven toothpastes with different composition designed for early childhood were studied. Identification of detected microorganisms was carried out via mass spectrometry. Antibacterial activity was determined by agar diffusion and serial dilution methods. Results. Toothpastes containing xylitol, lactic enzymes and ingredients of medicinal herbs exhibited the absence of a microbial growth inhibition zone. Fluoride toothpastes were active against all tested microorganisms, and the final fluoride inhibitory concentration was 0.00016-0.0025%, depending on the fluoride concentration in the toothpaste. Conclusion. The least pronounced antimicrobial activity was detected in complex toothpastes with lactic enzymes and ingredients of medicinal herbs, as well as in samples with xylitol. Simple toothpastes with organic and inorganic fluorine compounds demonstrated the best bactericidal effect.
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