Abstract
The incidence of infection by extended spectrum of s lactamase (ESBL)-producing bacteria is increasing throughout the world. Surveillance results in Indonesia (2012) showed that extended spectrum of s lactamase (ESBL) producing Escherichia coli was increased (52%). Streptomyces has become an important source of important bioactive compounds with high commercial value and continues to be routinely screened to look for new bioactive substances. The aims of this research is to screen in vitro antibacterial activity of the free cell fermentation Streptomyces sp. of Kalimantan acidic peatland (isolate 2.1). Streptomyces sp. have been isolated from Kalimantan Tengah peat soil (Palangka Raya). The isolatation and fermentation process to obtain antibaterial substances were performed in the International Streptomyces Projects (ISP)-4 media on rotary shaker at 150 rpm, 28C for 5 days. In vitro antibacterial testing of one to 5 days free cell fermentation broth (FCFB) of the Strepromyces sp. isolate 2.1 have been carried out by diffusion agar method. Antibacterial testing using the extended spectrum of s lactamase (ESBL) Escherichia coli isolated from Dr. Soetomo Hospital patients in Surabaya as test microorganisms. The results of this research is the FCFB of Streptomyces sp. isolate 2.1 showed its activities againts ESBL producing Escherichia coli 6024 and 6110 with inhibition zone average 12, 42 mm and 13, 17 mm. Conclusion of this research is Streptomyces sp. isolated Kalimantan acidic peatland (isolate 2.1) potent to againts ESBL producing Escherichia coli.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
