Abstract
In continuation of our phytochemical investigations of the Algerian flora [1,2], we studied Santolina chamaecyparissus L. a common species in the North regions of Algeria and Tunisia [3]. The aim of this study was to investigate the chemical composition of the essential oil of Santolina chamaecyparissus from Algeria and to evaluate its potential antimicrobial activity using the agar diffusion disc method against the following Gram-negative bacteria Pseudomonas aeruginosa (ATCC 9027), Escherichia coli (ATCC 4157), Klebsiella pneumonia (ATCC 4352), well as Gram-positive bacteria Staphylococcus aureus (ATCC 6538), Staphylococcus epidermis (ATCC 1228) and the fungi Candida albicans (ATCC 2601) [4]. The identification has been carried out by GC and GC-MS. The essential oil consisted of a complex mixture of 36 different substances, among them camphor (31.1%) and cubenol (17.0%) were the main compounds. The shapes of the kinetic curves of essential oil's extraction suggest that the essential oil is localized in endogenous and exogenous sites. The essential oil tested showed greater antibacterial and antifungal activities than positive controls.
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