Abstract

Pentacyclic triterpenes and crude extracts with antimicrobial activity from Cameroonian brown propolis samplesSakava Paul, Talla Emmanuel, Chelea Matchawe, Tchinda Tiabou Alembert, Zeuko’o Menkem Elisabeth, Laurent Sophie, Vander Elst Luce, Tagatsing Fotsing Maurice, Yaya Gbaweng Abel Joel, Atchade De Théodore Alex and Mbafor Tanyi Joseph

Highlights

  • Propolis, referred to as bee glue, is a red to dark brown sticky substance produced by bees and is composed of a resinous mixture of compounds (Stepanović et al, 2003; Ugur and Arslan, 2004)

  • The ethanolic extract of propolis obtained from Tabora displayed activity on almost all tested microorganisms (MIC 0.42 – 1.67 mg/ml) with only Pseudomonas aeruginosa being resistant to this extract

  • The observed minimum inhibitory concentrations (MICs) for both samples were several times higher when compared to a previous report on Tanzanian propolis (Seidel et al, 2008), where MICs ranged from 15.62 to 250 mg/l for Gram +ve bacteria

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Summary

Introduction

Referred to as bee glue, is a red to dark brown sticky substance produced by bees and is composed of a resinous mixture of compounds (Stepanović et al, 2003; Ugur and Arslan, 2004). These compounds are produced by bees from bee secretions, beeswax, plant exudates, and other plant parts collected from the surrounding flora (Bankova, 2005; Scazzocchio et al, 2006; Wiȩckiewicz et al, 2013). Propolis contains a variety of compounds, some of which are terpenes, flavonoids and other phenolics (Marcucci, 1995; Bankova et al, 2000). Runyoro et al / Journal of Applied Pharmaceutical Science 7 (01); 2017: 171-176

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