Abstract
Potential antimicrobial activity of follicular fluid and its selectivity remains open questions in field of human and animal reproduction. In our work we examine antimicrobial activity of porcine follicular fluid on coliform bacteria, as Gram-negative, and B. cereus, as Gram-positive, by incubation of different dilatations of bacteria with follicular fluid in cultivation medium and microbiological analysis followed by. According to our results, growth of coliform bacteria is stimulated by porcine follicular fluid and has an inhibitor effect on B. cereus, the most probably caused by lysozyme activity. Further study of the antimicrobial effect of follicular fluid against other strains and biochemical analysis in order to define its mechanism, are necessary. .
Highlights
Follicular fluid fills the follicle antrum, surrounds the oocyte and granulose cells, and contains steroids, gluco protein hormones, plasma proteins, mucopolysaccharides and enzymes
Results show that follicular fluid promotes the growth of coliform bacteria
In B2 and B4 (Figure 1.a) containing follicular fluid increased number of coliform bacteria colonies are noticed compared to B1 and B3 where there was no follicular fluid, and this is evident from results presented in table 1 3h after incubation
Summary
Follicular fluid fills the follicle antrum, surrounds the oocyte and granulose cells, and contains steroids, gluco protein hormones, plasma proteins, mucopolysaccharides and enzymes. It is especially rich in content of hyaluronic acid whose degradation products participate in signal transduction and activation of lymphocytes which leads to pro-inflammatory reaction. In all cyclic changes of the follicle, and composition of follicular fluid, besides this main role and immune endocrine interaction, presence of immunological agents still indicates the presence of antimicrobial trait of follicular fluid, so scientists have come up with the idea and basis for investigation and detection of main effectors, carriers of these traits, as well as potential selectivity in relation to Gram-positive and Gram-negative bacteria
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
