Abstract

In this study the antimicrobial activity of a mixture of plant extracts originating from five different plants and suspended in three different forms of gel, cream and lotion was examined with the purpose of discovering new anti-microbial compounds. The antimicrobial activity was investigated through the standard disc diffusion method, as well as through a variation of the microdillution method. The formulations under examination (gel, cream and lotion) showed a broad spectrum of action against all the selected microorganisms, with inhibition zones of 9–46 mm. The minimal inhibitory concentration (MIC) for all the formulations against the microorganisms in the study was in the range of 0.000761μg ml-1 to 0.125μg ml-1. The results of this study have clearly demonstrated that the mixture of plant extracts originating from five different plants and suspended in the forms of gel, cream and lotion can definitely be used in the battle against the microorganisms under investigation.

Highlights

  • For a long period of time, plants have been a valuable source of natural products for maintaining human health, especially in the last decade, with more intensive studies for natural therapies

  • Antimicrobial activities of mixtures from different plant extracts were tested against 6 microorganisms, including 4 strains of bacteria: Escherichia coli ATCC 8739, Staphylococcus aureus ATCC 6538, Bacillus subtilis ATCC 6633, Streptococcus pyogenes and 2 species of fungi: Candida albicans ATCC 10231 and Aspergillus niger ATCC 16404

  • The aim of this study was to evaluate the antimicrobial properties of mixture from five different plant extracts in gel, cream and body milk formulation, against six different microorganisms

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Summary

Original scientific paper

ANTIMICROBIAL ACTIVITY OF MIXTURE FROM DIFFERENT PLANT EXTRACTS IN GEL, CREAM AND BODY MILK FORMULATION, AGAINST DIFFERENT MICROORGANISMS. In this study the antimicrobial activity of a mixture of plant extracts originating from five different plants and suspended in three different forms of gel, cream and lotion was examined with the purpose of discovering new antimicrobial compounds. The antimicrobial activity was investigated through the standard disc diffusion method, as well as through a variation of the microdillution method. The formulations under examination (gel, cream and lotion) showed a broad spectrum of action against all the selected microorganisms, with inhibition zones of 9–46 mm. The results of this study have clearly demonstrated that the mixture of plant extracts originating from five different plants and suspended in the forms of gel, cream and lotion can definitely be used in the battle against the microorganisms under investigation

INTRODUCTION
Plant materials
Suspension preparation
Test microorganisms
RESULTS AND DISCUSSION
Aspergillus niger ATCC
No growth of microorganism Growth of microorganism
Full Text
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