Abstract

We report for the first time on the antimicrobial activity of MgB2 powders produced via the Reactive Liquid Infiltration (RLI) process. Samples with MgB2 wt.% ranging from 2% to 99% were obtained and characterized, observing different levels of grain aggregation and of impurity phases. Their antimicrobial activity was tested against Staphylococcus aureus ATCC BAA 1026, Enterococcus faecalis ATCC 29212, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, and Candida albicans ATCC 10231. A general correlation is observed between the antibacterial activity and the MgB2 wt.%, but the sample microstructure also appears to be very important. RLI-MgB2 powders show better performances compared to commercial powders against microbial strains in the planktonic form, and their activity against biofilms is also very similar.

Highlights

  • Since the discovery of its superconducting properties [1], MgB2 has attracted a lot of interest both from the theoretical [2,3,4], and from the practical point of view, with many applications that have been explored and sometimes commercially developed and delivered to the market [5,6,7,8,9,10]

  • In the specific field of antimicrobial materials, it has been shown that the growth of biofilms formed by the Escherichia coli Gram-negative strain is strongly inhibited on MgB2 substrates

  • Sample compositions were investigated by means of the X-ray diffraction (XRD), EDX, and thermogravimetry and differential scanning calorimetry (TG/DSC) techniques, obtaining self-consistent and reliable results

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Summary

Introduction

Since the discovery of its superconducting properties [1], MgB2 has attracted a lot of interest both from the theoretical [2,3,4], and from the practical point of view, with many applications that have been explored and sometimes commercially developed and delivered to the market [5,6,7,8,9,10] Preparation methods for this material span a large variety of different techniques [11,12,13,14,15,16,17,18,19,20,21,22,23], and among them the Reactive Liquid Infiltration (RLI). The present paper is dedicated to fill this knowledge gap by assessing the physico-chemical and the bioactivity properties of MgB2 samples produced via RLI

Experimental
Results and Discussion
Representative
Panel the remaining four strainsfour and six samples in Figure
Conclusions
Methods

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