Abstract
Objective: To screen the antimicrobial activity of different extracts of leaves of Artemisia vulgaris. Materials and Methods: To detect the in vitro antibacterial activity, 10 bacterial strains were selected. These bacteria are both gram +ve and gram -ve. Leaves were extracted with a petroleum ether, chloroform, ethyl acetate, ethanol and aqueous . In the present work the antibacterial activity was done by cup plate method. The antibacterial activity was expressed as zone diameter in millimeters. Different extracts from leaves of the plant was compared with standards like benzyl penicillin for gram +ve bacteria and streptomycin for gram –ve bacteria using DMF as control. The readymade media for inoculum and culture was obtained from Himedia labs. For antifungal activity four fungal organisms were selected and Griseofulvin was used as standard. Results: Herbal extracts prepared from the leaves of the plant were screened against bacteria and fungal organisms at the concentration range between 50 µg and 300 µg/0.1ml. The results of antimicrobial activity revealed that the extract exhibited activity against both gram +ve, gram –ve and fungal organisms. Conclusion: The present investigation reveals that the aqueous, chloroform and ethyl acetate extracts and in some cases petroleum ether extract showed significant antimicrobial activity when compared with standard.
Highlights
Introduction to Plant & Review of Literature Pharmacognostic Study Material and MethodsAntibacterial activity activity Antifungal activity
Different extracts from leaves of the plant was compared with standards like benzyl penicillin for gram +ve bacteria and streptomycin for gram –ve bacteria using DiMethyl Formamide (DMF) as control
The present investigation reveals that the aqueous, chloroform and ethyl acetate extracts and in some cases petroleum ether extract showed significant antimicrobial activity when compared with standard
Summary
Artemisia vulgaris is an aromatic perennial shrub belonging to family Asteraceae. Synonyms: Artemisia nilagirica Hernandez H and et al Aqueous extract of Artemisia vulgaris showed a 89.8% growth inhibition of the Plasmodium falciparum in In-vitro culture Abdual Ghani AS and et al. The effect of aqueous extract of leaves and stems of Artemisia vulgaris were studied on picrotoxin induced seizures in mice. Uniyal GC and et al The essential oil of aerial parts of plant constituents were camphor, betaeudesmol, 1,8-cineole, borneol, Artemisia alcohol, camphene, alpha-gurjunene, pcymene, terpinene-4-ol and -pinene Marco JA and et al. The aerial parts of Artemisia vulgaris yielded two new eudesmane acids and a known eudesmane dialcohol Worner M et al.[54] volatile constituents was fractionated from solid liquid extraction with pentane dichlomethane. Milhau G et al Essential oil of Artemisia vulgaris were showing In-vitro antimalarial activity on Plasmodium falciparum.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
