Abstract
Kalanchoe pinnata (synonym to Byrophyllum pinnatum) or commonly known as “Setawar” is a medicinal plant belongs to the Crassulaceae family. It is also known as “life plant” and “resurrection plant” due to its multiple roles in traditional medication. The therapeutic values of K. pinnata mostly lie on the presence of phytochemicals or plant active compounds which possess high potential as a natural antimicrobial agent source. Given the global health threat of antimicrobial resistance towards synthetic drugs, uncovering the natural sources as a novel drug is of crucial need. In this regard this review highlights the antimicrobial property of K. pinnata extract, the bioactive compound analysis of this plant extract and their mode of action against pathogenic microorganisms. The potent bioactive compounds extracted from K. pinnata plant could be further explored as an alternative medicine to the current synthetic antimicrobial drugs.
Highlights
The search for potent antimicrobial agents has been shifted to plants
In the study to determine the effects of extraction solvents, methanol, chloroform, petroleum ether, acetone and ethyl acetate on K. pinnata antimicrobial activity against several pathogens, methanolic extract from leaves part revealed the highest activity toward tested microorganisms
The present review briefly discusses the wide variety of bioactive compounds in the K. pinnata that exhibit antimicrobial activity against several pathogens and their modes of action
Summary
The search for potent antimicrobial agents has been shifted to plants. Some plants are medicinally practical in treating disease as the efficiency of antimicrobial property of certain plants is astonishingly great in most cases [1]. Diseases caused by resistant bacteria often fail to respond to conventional therapy, which causes prolonged illness and amplify the risk of death This severe issue spurs a greater need for more potent plant-mediated antimicrobial agents, alongside uncovering the active ingredients that can act as a template to generate new antimicrobial drugs. The presence of bioactive compounds within this plant indicates its antimicrobial activity against pathogenic microorganisms and holds various therapeutic benefits, making it a good alternative for the current synthetic antibiotics [6]. This review paper focuses on the antimicrobial activity of K. pinnata bioactive molecules in terms of antibacterial, antifungal and antiviral properties. It presents the analysis of active compounds directly involved in antimicrobial activities. The mechanism of action of the bioactive compounds against pathogens is briefly discussed
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