Antimicrobial Activity of Crude Extracts of Endophytic Fungi Isolated from Medicinal Plant Trichilia elegans A. Juss

Rhoden Rhoden

doi:10.7324/japs.2012.2807

Abstract

Antimicrobial Activity of Crude Extracts of Endophytic Fungi Isolated from Medicinal Plant Trichilia elegans A. Juss

Highlights

All microorganisms that inhabit, at least for one period of their life cycle, the interior of higher plants, may be considered as an endophyte (Azevedo et al, 2000)
The aim of the present work was to investigate biotechnological potential of fungal endophytes (Cordyceps memorabilis, Phomopsis longicolla, Dothideomycete sp. and one non-indentified) isolated from T. elegans, that have been assayed against five pathogenic bacteria
The antimicrobial activity from endophytes isolated of T. elegans G4-2 (Cordyceps memorabilis), G9-10 (Phomopsis longicollaG8-25 and G5-32 (Dothideomycete sp.) obtained through fermentation and extraction with ethyl acetate and through incubation of the mycelium with methanol was tested against five pathogenic bacteria (Table1).When the metabolic extracts of the endophytic fungi, obtained through the mycelium incubation with methanol, were assessed, it was verified that no extract had differed from the control regarding the antimicrobial activity

Summary

Introduction

At least for one period of their life cycle, the interior of higher plants, may be considered as an endophyte (Azevedo et al, 2000). These microorganisms can have a biotechnological potential mainly on antimicrobial activity (Molina et al, 2012). The production of metabolites by microorganisms is known and explored, because the major of antibiotics are produced by fungi and bacteria (Strobel, 2003), in this way,antimicrobial activities have been demonstrated in a variety of metabolites biosynthesized by the plant endophytes (Strobel et al, 2001). Many studies have shown that some medicinal properties of plants may be related to endophytic fungi hosted by these plants (Azevedo et al, 2000)

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Results