Abstract

The bactericidal and bacteriostatic properties (in darkness) of salts RE(NO3)3 · xH2O (RE = La, Ce, Gd, Yb, Y) and composite hydrogels with poly(N-vinylpyrrolidone) against Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Proteus mirabilis, and Klebsiella pneumonia bacteria and Candida albicans fungi have been analyzed. A correlation between the regions of delayed growth of microorganisms and the object characteristics is proposed. The mechanisms of interaction of Yb3+ ions of Yb(NO3)3 · xH2O salt, which exhibit high antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans with bacterial cell walls are demonstrated on ordered phospholipid monolayers (a model of biological membranes).

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