Abstract

Background: Azadirachta indica is a multipurpose tree called as Neem which is used in Ayurvedic medicine for skin infections and household pesticide. Methods: Aqueous extraction of plant material such as leaf and stem bark were investigated for anti-microbial activity without altering con centration. Results: Results of study revealed that all extracts had inhibitory activity against Staphylococcus aureus with the clear zone of 2.6cm, which is higher than streptomycin control. The inhibition zone was found descending order against Klebsiella, Psedumonas and Bacillus species. Antifungal activity of bark extract of Azadirachta indica against Aspergillus and Yeast showed the inhibitory growth of 64.2 % and 64% whereas the leaf extract showed less inhibition than bark extract. Conclusion: The findings reveal that bark and leaf aqueous extracts have wide-ranging activity.

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