Abstract
Buddleja salviifolia has been used as a food ingredient for improving digestion, antiemetic, to relieve coughs, colic and constipation. B. salviifolia has also been used in traditional medicine to treat varieties of diseases, which include eye infections, tuberculosis (TB), cervical cancer, syphilis, neurodegenerative conditions. A few articles on the antimicrobial activities of extracts from leaves of B. salviifolia have previously been reported. However, the antimicrobial activities of hexane, chloroform, ethyl acetate and methanolic extracts from the leaves and stem-bark of B. salviifolia have not been reported previously. Therefore, in the present study, we evaluated the antimicrobial activities of these extracts against six bacterial isolates viz. Escherichia coli (wild strain), Escherichia coli (O157:H7), Listeria monocytogenes, Staphylococcus aureus, Serratia marcescens and Pseudomonas aeruginosa and two fungal isolates viz. Penicillium digitatum and Candida albicans. Their inhibition zones were found to be in the range of 7.0±1.4 to 36.5±7.8 mm against bacterial isolates and 7.0±0.0 to 22.0±1.4 mm against fungal isolates. Additionally, the MIC values of these extracts were found to be in the range of <31.25 to >1000 µg/mL against both bacterial and fungal isolates. To conclude, extracts from B. salviifolia exhibited promising antimicrobial activities. Since B. salviifolia has wide verities of applications as a food ingredient and in the traditional medicine, further studies on various parts of this plant will be useful to commercialize products.
Highlights
Buddleja salviifolia belongs to the Scrophulariaceae family of the Buddleja genus (Van Wyk and Van Wyk, 1997; Tank et al, 2006; Van Laere et al, 2011)
A total of six bacterial isolates (four Gram-negative bacteria viz. E. coli, E. coli O157: H7, S. marcescens and P. aeruginosa), and two fungal isolates viz. P. digitatum and C. albicans were used in this study to evaluate the antimicrobial activities of the various extracts from the leaves and stem -bark of B. salviifolia
We evaluated antibacterial and antifungal activities of hexane, chloroform, ethyl acetate, methanol extracts from leaves and stem-bark of B. salviifolia
Summary
Buddleja salviifolia belongs to the Scrophulariaceae family of the Buddleja genus (Van Wyk and Van Wyk, 1997; Tank et al, 2006; Van Laere et al, 2011). Our literature search showed that a 20% methanolic crude extract obtained from the leaves of B. salviifolia and its hexane, dichloromethane, ethyl acetate, and butanol fractions have previously been studied for their antimicrobial activities against Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumoniae and Candida albicans (Pendota et al, 2013). To the best of our knowledge, hexane, chloroform, ethyl acetate, and 100% methanolic crude extracts from the leaves and stem-bark of this plant have not been explored well for their antimicrobial studies. The aim of the present study was to evaluate the antibacterial and antifungal activities of hexane, chloroform, ethyl acetate and methanol extracts from leaves and stem-bark of B. salviifolia against six bacterial isolates viz. E_coli (wild strain), E. coli O157: H7, L. monocytogenes, S. aureus, Serratia marcescens and Pseudomonas aeruginosa and two fungal isolates viz. Penicillium digitatum and C. albicans
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