Abstract
drugs has been cited both in the treatment of human brucellosis and in experimental brucellosis of laboratory animals. Synergistic activity of a combination of streptomycin and sulfadiazine has been reported by Pulaski and Amspacher (1947), Eisele and McCullough (1947), and Spink et al (1948) in the treatment of human brucellosis, and by Shaffer and Spink (1948) and Carle and Larson (1950) in experimental brucellosis of laboratory animals. The value of a combination of dihydrostreptomycin and aureomycin has been reported by Herrell and Barber (1949 and 1950) in the treatment of human brucellosis, and by Magoffin et al (1949), Heilman (1949), Carle and Larson (1950), and Werner and Knight (1950) in experimentally infected laboratory animals. Eisele and McCullough (1949, 1950a and b) have used a combination of dihydrostreptomycin, aureomycin, and
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