Abstract

The anti-inflammatory activity of ethanolic root extract of Aconitum heterophyllum(225, 450 and 900 mg/kg p.o) has been evaluated in cotton pellet-induced granuloma in rats. The extract has reduced inflammation as evidenced by decreased weight of cotton pellet in cotton pellet-induced granuloma in rats. The results demonstrate the anti-inflammatory properties of extract and the effects were comparable to diclofenac sodium, a standard non-steroidal anti-inflammatory drug. Key words: Aconitum heterophyllum, cotton-pellet, inflammation.

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