Abstract
The article considers I and II generation of antihistamines (AGs), which are used today in medical practice. The advantages of nonsedative II generation of AGs, especially socalled active metabolites (fexofenadine, cetirizine, levocetirizine, desloratadine) are emphasized. Currently, AGs, such as fexofenadine is deservedly regarded. This is one of the most effective H1AG for therapeutic practice that combines high efficacy and safety. This is the first choice treatment for allergic rhinitis patients.
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