Abstract
Antifungal screening of 61 folkloric medicinal plant extracts against dermatophytic fungi Trichophyton rubrum
Highlights
Pancreatic cancer remains as one of the most aggressive cancer in the world, with 280000 and 338000 new cases diagnosed in 2008 and 2012 respectively (Ferlay et al, 2013, 2010)
Annona muricata Linn has been reported to contain valuable bioactive compounds known as Annonaceous acetogenins.Theselong chain fatty acids were widely discussed for its potential in promoting anticancer and antiproliferative activity in various cancer cell lines
The data demonstrate that A. muricata hexane and commercialized extracts induced mild cytotoxicity in pancreatic cancer cells (Capan-1)
Summary
Pancreatic cancer remains as one of the most aggressive cancer in the world, with 280000 and 338000 new cases diagnosed in 2008 and 2012 respectively (Ferlay et al, 2013, 2010) These numbers accounts for only 3% of all types of cancer, pancreatic cancer continues topping the chart as a top leading cause of cancer mortality and it has recorded the highest death rate compared to other cancers (Hidalgo, 2010; Siegel et al, 2012). The highly sought effects are most probably induced by its major bioactive components known as annonaceous acetogenins (ACGs)
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