Abstract
1 Faculty of Medicine, Universiti Sultan Zainal Abidin (UniSZA), Medical Campus, Jalan Sultan Mahmud, 20400 Kuala Terengganu, Terengganu, Malaysia 2 Faculty of Health Sciences, UniSZA, Gong Badak Campus, 21300, Kuala Terengganu, Terengganu, Malaysia. 3 Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150, Kubang Kerian, Kelantan, Malaysia.
Highlights
C. albicans is the most common cause of human candidiasis
The objective of this study was to evaluate the antifungal properties of MTH and SBP against C. albicans and C. neoformans
Different concentrations of the MTH and propolis (0.78 mg/mL – 50.00 mg/mL) in two-fold dilutions were tested against each fungus to determine the Minimum Inhibitory Concentration (MIC) which was done by visual inspection and spectrophotometric (MIC95) reading at 620 nm
Summary
It is part of the human normal flora of the skin, mucous membranes, and gastrointestinal tract It is commonly responsible for opportunistic infections in immunocompromised patients or patients who are undergoing therapy with broad-spectrum antibiotics or in those with certain physiological disorders (Kourkoumpetis et al, 2010; Sobel, 2007; Nucci et al, 2010). The common side effects of amphotericin B and flucytosine include diarrhea, headache, indigestion, loss of appetite, nausea, vomiting and abdominal pain. Besides that, these drugs can cause renal toxicity
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