Antifungal effectiveness test fragrant leaf ethanol extract (Pandanus Amaryllifolium Robx) against fungus Pityrosporum Ovale in vitro

Abstract

Dandruff is one of the fungal infection problems that causes lack of confidence and discomfort due to complaints of itching that accompanies it. The fungus that causes dandruff is Pityrosporum ovale. Pityrosporum ovale has been reported to be resistant to the use of these azole drugs. One of the plants that has the potential as herbal medicine is pandan leaves (Pandanus amaryllifolius Roxb). The purpose of this study was to determine the antifungal activity of fragrant pandan leaf extract (Pandanus amaryllifolius Roxb) on the growth of Pityrosporum ovale in vitro. The research method used an experimental method with the extract concentrations used were 10%, 20%, 30%, and 40%. The antifungal testing method uses the agar diffusion method using the Kirby Bauer method. The results showed that pandan fragrant leaf extract with concentrations of 10%, 20%, 30% and 40% had moderate strength antifungal inhibition against Pityrosporum ovale. The largest inhibition zone was at a concentration of 40%, which was 9.43 mm. This indicates that the fragrant pandan leaf extract has antifungal effect on Pityrosporum ovale which causes dandruff. So that the results of this study can be used as a product to reduce the problem of dandruff.