Abstract
Yellow chrysanthemum (Chrysanthemum segetum) contain secondary metabolites that have potential as antifungals. This study aims to determine the antifungal activity of the ethanol extract of yellow chrysanthemum leaves against Candida albicans and Pityrosporum ovale. This research included sample collection, preparation of dry samples, characterization of dry samples, extraction by maceration method using 96% ethanol, phytochemical screening, and antifungal tests using the agar diffusion method, as well as a positive control of 2% ketoconazole against Candida albicans and Pityrosporum ovale. The result is that ethanol extracts of yellow chrysanthemum leaves contain alkaloids, flavonoids, glycosides, saponins, tannins, and steroids. The minimum inhibitory concentration (MIC) of the ethanol extract of yellow chrysanthemum leaves was 50 mg/ml with an inhibition diameter of 10.20 mm for Candida albicans and 9.86 mm for Pityrosporum ovale. Ethanol extracts of yellow chrysanthemum leaves have antifungal activity against Candida albicans and Pityrosporum ovale.
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