Abstract
Although metal-organic frameworks (MOFs) or porous coordination polymers have been widely studied, their antimicrobial activities have not yet been fully investigated. In this work, antifungal activity of copper-based benzene-tricarboxylate MOF (Cu-BTC MOF), which is water stable and industrially interesting, is investigated against Candida albicans, Aspergillus niger, Aspergillus oryzae and Fusarium oxysporum. The Cu-BTC MOF can effectively inhibit the growth rate of C. albicans and remarkably inhibit the spore growth of A. niger, A. oryzae and F. oxysporum. This finding shows the potential of using Cu-BTC MOF as a strong biocidal material against representative yeasts and moulds that are commonly found in the food and agricultural industries.
Highlights
Metal-organic frameworks (MOFs) or porous coordination polymers are a group of highly porous crystalline materials consisting of metal clusters interconnected with organic linkers [1,2,3,4,5,6]
After 2 g Cu-BTC was immersed in 50 ml deionized water for a week and filtered by vacuum filtration, the wavelength-dispersive X-ray fluorescent spectroscopy (WDXRF) of the filtered water shows no copper indicating that the Cu-BTC is water stable
The morphology of the as-synthesized Cu-BTC was investigated by field-emission scanning electron microscopy (FE-SEM) and transmission electron microscopy (TEM) as shown in figure 1
Summary
Metal-organic frameworks (MOFs) or porous coordination polymers are a group of highly porous crystalline materials consisting of metal clusters interconnected with organic linkers [1,2,3,4,5,6]. Owing to their high surface area and other tunable properties, they have been extensively investigating in many applications since their discovery [1,5,6].
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