Abstract
ABSTRACT This study evaluated the antifungal activity of the traditional medicinal plants used by agricultural workers to treat onychomycosis. Of all tested plants, methanol leaf extracts of Croton tiglium possessed antifungal activity against many isolates. Azulene, 9-Hexadecenoic acid, Octadecane, and 3-ethyl-5-(2-ethylbutyl) were the major antifungal compounds identified by GC-MS/MS. Broad ranges of antifungal properties of C. tiglium makes it a potential candidate for the treatment of onychomycosis without health hazard.
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