Abstract
Objective: The present study was carried out to determine the antifungal activity of Mangifera indica leaves extract on fungi isolated from bread vended within Bakori.
 Methods: The powdered form of M. indica leaves was used to prepare the extract using ethanol, the leaves were air dried at room temperature for 10 days.
 Results: The chemical test was carried out to identify the secondary metabolites, some of the metabolites that were present include alkaloids, saponins, flavonoids, steroids, and tannins. Both fungal isolates were identified on the basis of morphological characteristics as Aspergillus niger, Aspergillus flavus, and Mucor spp. The antifungal activity of M. indica leaves extract was determined using agar well diffusion method on Aspergillus and Mucor spp. The results showed that the extract was found to inhibit A. niger at 100 mg/ml, 50 mg/ml, and 25 mg/ml with 13.9 mm, 11.5 mm, and 8.0 mm, respectively, and A. flavus at 100 mg/ml, 50 mg/ml, and 25 mg/ml with 13.6 mm, 11.2 mm, and 8.1 mm, respectively, while Mucor spp. was found to be resistant at 25 mg/ml while 100 mg/ml and 50 mg/ml showed an activity. Minimum inhibitory concentration result showed a promising activity against Aspergillus spp. at 25 mg/ml while Mucor spp. at 50 mg/ml.
 Conclusion: Therefore, M. indica leaf extracts can be used in the treatment of diseases or illness caused by Aspergillus and Mucor spp.
Highlights
Pathogenic fungi are the main infectious agents in plants, causing alterations during developmental stages including post-harvest
M. indica leave extract was kept in sterile bottle before phytochemical screening and antifungal determination [7]
Phytochemical screening of M. indica leaf extract The result of phytochemical screening of M. indica leaf extract was studied
Summary
Pathogenic fungi are the main infectious agents in plants, causing alterations during developmental stages including post-harvest. The plant kingdom provided a variety of compounds of known therapeutic properties, such as analgesic, anti-inflammatories, medicines for asthma, and others. Antimicrobial properties of plant extracts have been reported with increasing frequency from different parts of the world [3,4,5]. There is a little evidence on the antimicrobial activities of medicinal plants under investigation against phytopathogenic fungi. The medicinal value of these plants lies in some chemical active substances that produce a definite physiological active on the human body. The most important of these chemical active (bioactive) constituents of plants are alkaloids, tannin, flavonoid, and phenolic compounds. Many of these indigenous medicinal plants are used for medicinal purposes [6]
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