Antifungal Activities of Commercial Rice Wine Extracts of Taiwanese &amp;lt;i&amp;gt;Allium fistulosum&amp;lt;/i&amp;gt;

Tsan-Chang Chang,Peng-Fu Duan,Wang-De Lin,Hung-Der Jang

doi:10.4236/aim.2016.67046

Abstract

Antifungal activities of the commercial rice wine extracts of Allium fistulosum were analyzed. Antifungal activities were tested against 7 pathogenic fungi by using agar disc diffusion and tube dilution tests. The results show that the commercial rice wine extracts of Allium fistulosum have strong antifungal activity against Aspergillus brasiliensis ATCC 16404, Candida albicans ATCC 10231, Microsporumcanis ATCC 36299, M. gypseum ATCC 24102, Trichophyton mentagrophytes ATCC 9533, T. rubrum ATCC 28188, and T. tonsurans ATCC 28942. The commercial rice wine extracts of different A. fistulosum parts were found to exhibit significant antifungal activities with the minimal inhibitory concentration (MIC) in the range of 0.2 - 1.0 mg/mL. The antifungal activity of the extracts of different A. fistulosum parts was in the order of AFS (stem) > AFI (plant body) > AFL (leaf) > AFR (root).

Highlights

Pathogenic fungi often cause nosocomial infection and invade the keratinized tissues of humans and animalsHow to cite this paper: Chang, T.-C., Jang, H.-D., Lin, W.-D. and Duan, P.-F. (2016) Antifungal Activities of Commercial Rice Wine Extracts of Taiwanese Allium fistulosum
The results show that the extraction yields of A. fistulosum plant (AFI), A. fistulosum stem (AFS), and A. fistulosum leaf (AFL) was 42.3%, 43.6%, 42.4%, respectively, which are higher than those of A. fistulosum root (AFR) (15.5%)
The results suggested that allicin exhibited good fungicidal activity against all the test fungi except C. albicans

Summary

Introduction

Pathogenic fungi often cause nosocomial infection and invade the keratinized tissues of humans and animalsHow to cite this paper: Chang, T.-C., Jang, H.-D., Lin, W.-D. and Duan, P.-F. (2016) Antifungal Activities of Commercial Rice Wine Extracts of Taiwanese Allium fistulosum. Pathogenic fungi often cause nosocomial infection and invade the keratinized tissues of humans and animals. Opportunistic fungal infections are difficult to treat in immunocompromised patients, such as transplant patients, AIDS patients, cancer patients, and other immunocompromised hosts; approximately 40% of systemic infections result in serious consequences, such as death [1] [2]. Dermatophytes that grow on skin, mucous membranes, hair, nails, feathers, and other body surfaces cause ringworm and related diseases. A variety of pathogenic fungi, such as Aspergillus sp. Candida albicans, secrete mycotoxins and cause allergic reactions and localized or systemic infection [1]-[3]. A limited number of antifungal agents (such as polyenes and azoles) are currently available for the treatment of life-threatening fungal infections in modern medicine; very few antifungal agents from natural products could effectively suppressed of pathogenic fungi

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Conclusion