Antifeedant, larvicidal and growth inhibitory bioactivities of novel polyketide metabolite isolated from Streptomyces sp. AP-123 against Helicoverpa armigera and Spodoptera litura

Mariadhas Valan Arasu,Valsalam Saritha,Sun-Ju Kim,Naif Abdullah Al-Dhabi,Chinnasamy Muthukumar,Veeramuthu Duraipandiyan

doi:10.1186/1471-2180-13-105

Mariadhas Valan Arasu, Valsalam Saritha + Show 4 more

Open Access

https://doi.org/10.1186/1471-2180-13-105

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Abstract

BackgroundConsiderable attention has been paid to actinomycetes, especially the secondary metabolites obtained from Streptomyces species, as the best alternatives to chemicals as biological control agents for polyphagous pests such as Helicoverpa armigera and Spodoptera litura. On the basis of their novel biocontrol attributes, novel polyketide metabolite isolated from marine Streptomyces sp. AP-123 exhibited significant antifeedant, larvicidal and growth inhibitory activities against polyphagous pests.ResultsLeaf disc no-choice method was used for the insect bioassay. The polyketide metabolite presented significant antifeedant activities against H. armigera (78.51%) and S. litura (70.75%) at 1000 ppm concentration. The metabolite also exhibited high larvicidal activities against H. armigera (63.11%) and S. litura (58.22%) and the LC50 values were 645.25 ppm for H. armigera and 806.54 ppm for S. litura. The metabolite also prolonged the larval–pupal duration of the insects at all the tested concentrations.ConclusionsThe activities of the polyketide metabolite were concentration dependent for both the insects therefore it could be used as an agent to prepare new pesticidal formulations.

Highlights

Considerable attention has been paid to actinomycetes, especially the secondary metabolites obtained from Streptomyces species, as the best alternatives to chemicals as biological control agents for polyphagous pests such as Helicoverpa armigera and Spodoptera litura
In the present study, polyketide metabolite derived from Streptomyces sp
AP-123 revealed strong antifeedant activity of 78.51% and 70.75% against H. armigera and S. litura, respectively at 1000 ppm concentration and the activity was statistically significant over control (P ≤ 0.05) (Table 1)

Summary

Introduction

Considerable attention has been paid to actinomycetes, especially the secondary metabolites obtained from Streptomyces species, as the best alternatives to chemicals as biological control agents for polyphagous pests such as Helicoverpa armigera and Spodoptera litura. Helicoverpa armigera and Spodoptera litura are the major polyphagous pests attacking more than 150 different host species and affect the vegetable yield [2]. These pests are considered as the most economically important insect pests in many countries including India, Japan, China and Southeast Asia. Controlling these polyphagous pests becomes the challenging work in agriculture field. Biopesticides have been gaining increased attention and interest among those concerned with developing environment friendly and safe integrated crop management, with compatible approaches and tactics for pest management [5]

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