Abstract
These researchers aimed to clarify the risk for congenital malformations in offspring of women with epilepsy treated with antiepileptic drugs (AEDs). Using a large, population-based database in Finland that records pharmaceutical reimbursements, available to all citizens, the researchers identified all women with epilepsy who were eligible to receive full reimbursement for AEDs over a 9-year period. The researchers retrospectively identified 2450 children born to this cohort and reviewed their records for evidence of any congenital malformation. They compared risks associated with (1) use during the …
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