Abstract
Diuretic activities of both polar and non-polar extract of leaves of Brassica oleracea were investigated on male white rabbits and male Sprague-Dawley rats. Anti diarrheal activity of the same extract was investigated on male and female swiss albino mice. Both polar and non-polar extract exhibited anti diuretic activities on both rats and rabbits. Polar and Non-polar extract also showed anti diarrheal activity on male and female mice. Anti diarrheal activity affects both latent period and number of stools.
Highlights
Brassica oleraceae var. capitata (Brassicaceae) is round shape in size and is composed of leaf layers that are imposed one after another
Aqueous extract of the capitata variety of B. oleracea shows antiulcerogenic property (Carvalho CA et al, 2011) whereas both aqueous and non-aqueous extract of acephala DC variety provide protection from the oxidation of LDL and VLDL resulting in improvement of cardiovascular diseases (Kural BV et al, 2011)
Mechanism of anti diuretic function might follow prostaglandin pathway in which both polar and non-polar BOE inhibit prostaglandin on smooth muscle cells resulting in contraction of smooth muscle (Nelson RJ, 2005)
Summary
Brassica oleraceae var. capitata (Brassicaceae) is round shape in size and is composed of leaf layers that are imposed one after another. Capitata (Brassicaceae) is round shape in size and is composed of leaf layers that are imposed one after another It is a member of the food family traditionally known as cruciferous vegetables and is related to kale, broccoli, collards. It has a long history of using as a food and traditional treatment option in diarrhea (Gani, 2003). Antioxidant property (Eberhardt MV et al, 2005 & Bidchol AM et al, 2011) of B. oleraceae studied over which is responsible for its anticholinesterase activity (Boga M et al, 2011). The present study was designed to investigate anti diuretic activity of B. oleracea on rats and rabbits and anti diarrheal property of both polar (ethanolic) and non-polar (carbon tetrachloride) extract on swiss albino mice
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