Abstract
To study the utilization pattern of anti-diabetic drugs in type 2 diabetic patients and to evaluate the association of diabetes with demographic details and it's metabolic control. The study was carried out on 100 type 2 diabetic patients who visited AL- Nasiriya center for diabetes and endocrinology. Demographic details and complete prescriptions drugs, FBS (fasting blood sugar), HbA1c and BMI (body mass index) were recorded. A total of 100 type 2 diabetic patients, 27(27%) were males and 73(73%) were females. The greatest number of patients, 43%, were in the age group of 51-60 years. Obesity (BMI ≥ 30) were found in 51% of patients especially females 45(61.3%). Poor glycemic control (HbA1c ≥ 9) were found in 65% of the patients. Oral anti-diabetic drugs were prescribed in 53%, 16(60%) were males and 37 (50.6%) were females. Biguanide (metformin) alone, 22%, was the most common anti-diabetic drugs prescribed. Biguanides (metformin) and sulfonylurea combination, 19%, was the commonest anti-diabetic drugs combination. Insulin preparations alone were used in 23% of the patients and Novomix was the commonest type (10%). We concluded that oral anti-diabetic drugs were the most common prescribing drugs. Metformin was the commonest prescribing anti-diabetic drugs. Metformin and sulfonylurea being the most frequent combination prescribed. There were increasing in the use on insulin preparations in the treatment of type 2 diabetic patients. In achieving optimal glycemic control, the efficacy of anti-diabetic drugs was only 10%, planning of more intensification anti-diabetic treatment is necessary.
Highlights
Type 2 diabetes mellitus is a disease marked by high levels of blood glucose due to the action of insulin and insufficient insulin production
Diabetes mellitus (DM) is one of the oldest diseases known to man, which was the first reported in Egyptian literature about 3000 years ago [3]
Complications due to hyperglycemia in diabetes mellitus can be prevented by using rational use of oral antidiabetic drugs (OADs) and insulin [11]
Summary
Type 2 diabetes mellitus is a disease marked by high levels of blood glucose due to the action of insulin and insufficient insulin production. Complications due to hyperglycemia in diabetes mellitus can be prevented by using rational use of oral antidiabetic drugs (OADs) and insulin [11]. Various classes of anti-diabetic drugs including oral hypoglycemic agents (OHA) and insulin are currently used in the treatment of diabetes, which acts by different mechanisms to reduce the blood glucose levels to maintain optimal glycemic control [14, 15]. United Kingdom Prospective Diabetes Study (UKPDS) advocates for increasing requirement of multiple therapies in patients with type 2 diabetes to achieve blood glucose target control [20]. Diagnosed type 2 diabetic patients who do not receive pharmacological therapy, prediabetic status, diabetic complications and serious medical conditions requiring subsequent hospital admissions were excluded from the study
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
