Abstract
The present study was carried out to evaluate the anti-diabetic activity of polysaccharides from Agaricus bisporus mycelia (PABM) in alloxan-induced diabetes mellitus (DM) mice. After administration with 100, 200 and 400 mg/kg body weight of PABM to DM mice for 28 days, the effects of PABM on the body weight, blood glucose, serum insulin, total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) levels were monitored. The results showed that the PABM could increase body weight, serum insulin and HDL-C levels, as well as decrease TC, TG and LDL-C levels in DM mice. PABM possess anti-diabetic activity.
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